Table 3.

Overall Association between Age/Sex and Duration of Pre-hospital delay

	Men			Women			P value†	P value‡
	< 65 y	65–75 y	≥75 y	< 65 y	65–75 y	≥75 y
Difference in Median of Pre-hospital Delay (95% CIs), hours
Model 1	0 (reference)	0.12 (−0.07; 0.30)	0.62 (0.43; 0.81)	0.13 (−0.09; 0.36)	0.48 (0.27; 0.70)	0.4 (0.23;0.57)	0.001	0.004
Model 2	0 (reference)	0.12 (−0.13; 0.36)	0.55 (0.29; 0.82)	0.14 (−0.16; 0.44)	0.37 (0.07; 0.66)	0.37 (0.10;0.65)	0.10	0.18
Model 3	0 (reference)	0.11 (−0.10; 0.32)	0.61 (0.39; 0.84)	0.12 (−0.14; 0.37)	0.37 (0.21; 0.72)	0.31 (0.08;0.55)	0.001	0.69
Absolute Medians of Pre-hospital Delay (95% CIs), hours
Model 1	1.89 (1.78–1.99)	2.01 (1.85–2.15)	2.51 (2.35–2.66)	2.02 (1.82–2.22)	2.37 (2.18–2.56)	2.29 (2.15–2.42)	0.001	0.004
Model 2	1.94 (1.79–2.09)	2.06 (1.86–2.26)	2.49 (2.29–2.70)	2.08 (1.82–2.34)	2.31 (2.06–2.56)	2.31 (2.11–2.52)	0.10	0.18
Model 3	1.96 (1.83–2.09)	2.07 (1.90–2.24)	2.57 (2.40–2.75)	2.08 (1.85–2.30)	2.33 (2.22–2.63)	2.27 (2.10–2.45)	0.001	0.69

Model 1: Included age, sex, and study year.

Model 2: Further adjusted for race, marital status, and history of angina, diabetes, heart failure, hypertension, stroke, and CABG.

Model 3: Further adjusted for clinical presentation including day of week admission, time of day, chest pain, AMI order (intial vs. prior), AMI type (Q wave vs. non-Q wave), and AMI location (anterior vs. inferior/posterior).

Notes: Information on DNR and STEMI was recorded beginning in 1991 and 1997, respectively; therefore, they were not included as controlling variables in regression model #3.

^†p values for interaction between age and sex

^‡p values for interaction among age, sex, and study year