Fig. 4.

Cholesterol concentrations and rates of cholesterol synthesis in different regions of the brain. The central nervous system of 49 day-old male animals with the four different genotypes (n = 10–15 in each group) was dissected into five regions. The overall concentrations of cholesterol (A) and rates of cholesterol synthesis (B) in each whole-brain region were determined. Each column represents the mean ± SEM, and there were no significant differences (P > 0.05) among the tissues from the different genotypes.