Table 1.

Weinberger classification (2006)

Weinberger classification (2006)*
HPV status; p16 expression	Median HPV DNA viral load (copies HPV 16/human genome)
Class I, HPV-; p16 low	0.0 copies - Class I
Class II, HPV+; p16 low	3.6 copies - Class II
Class III, HPV+; p16 high	46.0 copies - Class III
Class IV, HPV-; p16 +

For further detail see the text

*according to the contents reported in: Weinberger PM, et al.: Molecular classification identifies a subset of human papillomavirus--associated oropharyngeal cancers with favorable prognosis. J Clin Oncol 2006, 24(5):736-47 [67]