Table 1.

Correlation between expression of ERCC1 and clinicopathological factors of HNSCC

		ERCC1		P	Multivariates analysis	P
	No. of patients	Low expression	High expression		OR (95% CI)
Age
≦50	22 (38.6%)	11 (50.0%)	11 (50.0%)	0.598	1
> 50	35 (61.4%)	20 (57.1%)	15 (42.9%)		0.47 (0.11, 2.11)	0315
Gender
Male	55 (96.5%)	30 (54.5%)	25 (45.5%)	1.000	1
Female	2 (3.5%)	1 (50%)	1 (50%)		48.36 (0.54, 4313.32)	0.090
Tumor Site
oral cavity	24 (42.1%)	11 (45.8%)	13 (54.2%)	0.057	1
oropharynx	21 (36.8%)	10 (47.6%)	11 (52.4%)		1.58 (0.35, 7.07)	0.549
hypopharynx/Larynx	12 (21.1%)	10 (83.3%)	2 (16.7%)		0.096 (0.007, 1.33)	0.081
Stage
IVa	10 (17.5%)	7 (70.0%)	3 (30.0%)	0.319	1
IVb	47(82.5%)	24 (51.1%)	23 (48.9%)		3.33 (0.39, 27.89)	0.276
T stage
1/2	6 (10.5%)	6 (100%)	0 (0%)	0.027*	1
3/4	51 (89.5%)	25 (49.0%)	26 (51.0%)		Indeterminate	0.999
N stage
negative	12 (21.1%)	5 (41.7%)	7 (58.3%)	0.503	1
positive	45 (78.9%)	26 (57.8%)	19 (42.2%)		0.75 (0.15, 3.64)	0.727
Alcohol drinking
Never	11 (17.2%)	4 (36.4%)	7 (63.6%)	0.318	1
Yes	46 (82.8%)	27 (58.7%)	19 (41.3%)		2.49 (0.31, 19.88)	0.388
Smoking
Never	9 (15.8%)	3 (33.3%)	6 (66.7%)	0.275	1
Yes	48 (84.2%)	28 (58.3%)	20 (41.7%)		1.77 (010, 30.72)	0.695
Betel nuts
Never	20 (35.1%)	8 (40.0%)	12 (60.0%)	0.109	1
Yes	37 (64.9%)	23 (62.2%)	14 (37.8%)		12.78 (1.28-127.62)	0.030*