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Effect of Acorus calamus on heat hyperalgesia assessed by the noxious thermal sensation evoked ipsilateral hind paw withdrawal threshold. Digits in parentheses indicate the dose of Acorus calamus and pregabalin in mg/kg. Data expressed as mean ± standard error of mean (SEM), each group consist of six (n = 6) Wistar rat. ap < 0.05 vs sham control group. bp < 0.05 vs CCI control group.
