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. 2011 Apr 7;7(4):e1001330. doi: 10.1371/journal.ppat.1001330

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Welz et al.

This is an open-access article distributed under the terms of the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original author and source are properly credited.

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The tree was calculated using Neighbour Joining method. Numbers at the branches indicate bootstrap values (in %, 1000 replicates). The bar shows number of substitutions per mutation site. The selected sequences (GenBank accession numbers in brackets) are as follows: C. elegans SLO-1a (AAL28102); C. elegans SLO-1b (AAL28103); C. elegans SLO-1c (AAL28104); C. briggsae hypothetical protein CBG12923 (XP_001675579.1); A. caninum SLO-1 (EU828635); C. oncophora SLO-1 (EF494185); H. contortus SLO-1 (EF494184); Ixodes scapularis putative calcium-activated potassium channel (EEC10339.1); Cancer borealis calcium-activated potassium channel (AAZ80093.4); Manduca sexta calcium-activated potassium channel alpha subunit (AAT44358.1); Pediculus humanus corporis putative calcium-activated potassium channel alpha subunit (EEB13088.1); Drosophila melanogaster slowpoke, isoform P (NP_001014652.1); Tribolium castaneum predicted protein similar to slowpoke CG10693-PQ (XP_968651.2); Aplysia californica high conductance calcium-activated potassium channel (AAR27959.1); Xenopus laevis potassium large conductance calcium-activated channel, subfamily M, alpha member 1 (NP_001079159.1); Danio rerio novel calcium activated potassium channel (CAX13266.1); Trachemys scripta calcium-activated potassium channel (AAC41281.1); Gallus gallus calcium-activated potassium channel alpha subunit (AAC35370.1); Monodelphis domestica predicted protein similar to large conductance calcium-activated potassium channel subfamily M alpha member 1 (XP_001367795.1); Mus musculus mSlo (AAA39746.1); Homo sapiens potassium large conductance calcium-activated channel, subfamily M, alpha member 1, isoform CRA_d (EAW54600.1); Bos taurus BK potassium ion channel isoform C (AAK54354.1); Canis familiaris calcium-activated K⁺ channel, subfamily M subunit alpha-1 (Q28265.2); Strongylocentrotus. purpuratus predicted protein similar to calcium-activated potassium channel alpha subunit (XP_783726.2).