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. 2011 Apr 7;7(4):e1001330. doi: 10.1371/journal.ppat.1001330

Figure 4. Parasite SLO-1 expressed from parasite-derived slo-1 promoters partially recover emodepside susceptibility in resistant slo-1 loss-of-function mutants.

Figure 4

Body bend activity (relative to the highest number of body bends in each group) of young adults after 24 h exposure to emodepside. Comparison of wild-type N2, emodepside-resistant strain slo-1(js379), and transformed slo-1(js379) lines. Dots (•) represent Aca-slo-1::Aca-slo-1 lines (expressing A. caninum slo-1 from the putative A. caninum slo-1 promoter); inverted triangles (▾) Con-slo-1::Con-slo-1 lines (expressing C. oncophora slo-1 from the putative C. oncophora slo-1 promoter); squares (▪) N2 Bristol wild-type strain, triangles (▴) js379(slo-1) mutant strain.