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. 2011 Apr 7;6(4):e18629. doi: 10.1371/journal.pone.0018629

Figure 1. Schematic of the structure of ASON-Bulge-DNAzyme.

Figure 1

A. Regular DNAzyme. B. ASON-Bulge-DNAzyme. A 15 base AS-ON was inserted at the 5′ end of “10-23”deoxyribozyme to target the mRNA substrate and an unmatched loop between the DNAzyme sequence and ASON sequence was designed.