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. Author manuscript; available in PMC: 2012 Mar 20.
Published in final edited form as: Proteins. 2010 Nov 30;79(3):787–802. doi: 10.1002/prot.22918

Table II.

Configurations corresponding to the ground states of the C5a receptors

Receptor, TM configuration TM1 TM2 TM3 TM4 TM5 TM6 TM7 Energy, kcal/mol
WT Rh 0 0 0 0 0 0 0 −540
A1 0 330 30 30 330 30 30 −557
A2 0 330 30 330 330 30 30 −551
A3 0 0 0 330 0 0 0 −564
A4 0 330 30 330 330 30 0 −545
NQ Rh 0 0 0 0 0 0 0 −513
A1 0 330 30 30 330 30 30 −546
A2 0 330 30 330 330 30 0 −552
A3 0 330 30 330 330 30 30 −553
A4 0 0 0 330 0 0 0 −540
A5 0 330 0 330 330 30 30 −544
A6 0 330 30 30 330 30 0 −538
A7 0 330 0 330 330 30 0 −536
NQ-N296A Rh 0 0 0 0 0 0 0 −508
A1 0 330 30 330 330 30 0 −556
A2 330 330 30 30 330 30 30 −539
F251A Rh 0 0 0 0 0 0 0 −506
A1 0 330 30 30 330 30 0 −539
A2 0 330 0 330 330 30 0 −531
A3 0 330 30 330 330 30 0 −540
A4 0 330 30 330 330 30 30 −542