Table VI.
Receptor, TM configuration | TM1 | TM2 | TM3 | TM4 | TM5 | TM6 | TM7 | Energy, kcal/mol | Connections | |
---|---|---|---|---|---|---|---|---|---|---|
N119S | A1 | 0 | 330 | 30 | 330 | 330 | 30 | 30 | −546 | A2/A3/B |
A2 | 0 | 0 | 0 | 330 | 0 | 0 | 0 | −566* | A1/A3 | |
A3 | 0 | 330 | 30 | 330 | 330 | 30 | 0 | −552 | A1/A2/B | |
B | 30 | 0 | 60 | 0 | 0 | 60 | 0 | −558 | A1/A3/CAM | |
CAM | 0 | 330 | 60 | 30 | 30 | 30 | 30 | −553 | B | |
R306 | A1 | 0 | 330 | 30 | 330 | 330 | 30 | 30 | −531 | A2/A3/B/C/D |
A2 | 0 | 0 | 0 | 330 | 0 | 0 | 0 | −545* | A1/A3 | |
A3 | 0 | 330 | 30 | 330 | 330 | 30 | 0 | −529 | A1/A2/B/C/D | |
B | 30 | 0 | 60 | 0 | 0 | 60 | 0 | −549 | A1/A3/CAM | |
C | 30 | 300 | 60 | 0 | 0 | 30 | 30 | −541 | A1/A3/CAM | |
D | 30 | 300 | 60 | 0 | 0 | 60 | 0 | −524 | A1/A3/CAM | |
CAM | 0 | 330 | 60 | 30 | 30 | 30 | 30 | −524 | B/C/D | |
R10 | A1 | 0 | 330 | 30 | 30 | 330 | 30 | 30 | −557* | A2/A3/B/C |
A2 | 0 | 330 | 30 | 30 | 330 | 30 | 0 | −537 | A1/A3/B/C | |
A3 | 330 | 330 | 30 | 30 | 330 | 30 | 30 | −548 | A1/A2 | |
B | 30 | 0 | 60 | 0 | 0 | 60 | 0 | −556 | A1/A3/CAM | |
C | 30 | 300 | 60 | 0 | 0 | 60 | 0 | −543 | A1/A3/CAM | |
CAM | 0 | 330 | 60 | 30 | 30 | 30 | 30 | −521 | B/C |