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. Author manuscript; available in PMC: 2012 Feb 20.
Published in final edited form as: Curr Opin Pharmacol. 2011 Feb 20;11(1):75–80. doi: 10.1016/j.coph.2011.01.010

Figure 2. Kinetic model of 5-HT3A receptor function.

Figure 2

The major states and transitions required to account for the actions of agonists on 5-HT3 receptors are shown in black. The minor transitions, which are shown in grey, are assumed to be possible, but negligible Values of rate constants (denoted above and below arrows) determined from macroscopic current experiments with rapid solution exchange are given in Solt et al. [40].