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. Author manuscript; available in PMC: 2012 Apr 15.
Published in final edited form as: Spine (Phila Pa 1976). 2011 Apr 15;36(8):E513–E518. doi: 10.1097/BRS.0b013e3181f52cb5

Figure 2.

Figure 2

Expression of the transgene and degeneration of the vertebral GP in tamoxifen-treated Col11 CAβ-catER mouse. A–D, Tissue sections of the tails from 6-weeks-old Col11 CAβ-catER mouse (B and D) and their WT littermates (A and C) were prepared and subjected to in situ hybridization for CAβ-catER transgene. E–J, Col11 CAβ-catER mice (F,H and J) and the WT littermates (E,G and I) received seven daily injections of tamoxifen (200 µg/20 µl/day). On the day following completion of the injections, the vertebrae were dissected and the tissue sections stained with HE (E–H) or Safranin O (I and J). The bar represents 150 °m for A–D, 300 µm for E, F, I and J, 75 µm for G and H.