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. Author manuscript; available in PMC: 2012 Apr 15.
Published in final edited form as: Spine (Phila Pa 1976). 2011 Apr 15;36(8):E513–E518. doi: 10.1097/BRS.0b013e3181f52cb5

Figure 4.

Figure 4

Disorganization of the IVD structure in tamoxifen-treated Col11 CAβ-catER mouse. Col11 CAβ-catER mice (B, D, F, H and J) and their WT littermates (A, C, E, G and I) received seven daily injections of tamoxifen (200 µg/20 µl/day). Four weeks after the treatment, the vertebrae were dissected. The tissue sections were prepared and subjected to HE (A, B, E and F) or Safranin O (C and D) staining, immunostaining for anti-BrdU antibody (G and H). A bar represents 300 µm for A–D, 150 µm for E and F, and 75 µm for G and H.