Table 1.
Genotype and Allele Frequencies of the HCRTR1 polymorphisms in migraine patients and controls
| GF | AF | ||||
|---|---|---|---|---|---|
| HCRTR1 SNP1 rs10914456 | C/C (%) | C/T (%) | T/T (%) | C (%) | T (%) |
| Controls | 108 (41.7) | 122 (47.1) | 29 (11.2) | 338 (65.3) | 180 (34.7) |
| Migraine patients | 146 (38.1) | 188 (49.0) | 50 (13.0) | 480 (62.5) | 288 (37.5) |
| HCRTR1 SNP2 rs4949449 | G/G (%) | G/T (%) | T/T (%) | G (%) | T (%) |
| Controls | 104 (40.2) | 129 (49.8) | 26 (10.0) | 337 (60.6) | 181 (39.4) |
| Migraine patients | 147 (38.3) | 190 (49.5) | 47 (12.2) | 484 (63.0) | 284 (37.0) |
| HCRTR1 SNP3 rs2271933 | G/G (%) | G/A (%) | A/A (%) | G (%) | A (%) |
| Controls | 125 (53.3) | 108 (41.7)a | 26 (10.0)a | 358 (69.1) | 160 (30.9)b |
| Migraine patients | 138 (36.0) | 194 (50.5) | 52 (13.5) | 470 (61.2) | 298 (38.8) |
p values were calculated by the χ 2 test from 3×2 (genotype) or 2×2 (allele) contingency tables
GF genotypic frequency, AF allelic frequency
a GF χ 2 = 9.872, p = 0.007, power = 0.819
b AF χ 2 = 8.108, p = 0.004, power = 0.828