Figure 2.

IL-13 responses to Schistosoma japonicum egg antigen predicts decreased liver span 1 year after praziquantel (PZQ) treatment. Peripheral blood mononuclear cells (PBMCs) from S. japonicum–infected individuals aged 7–30 years were collected 1 month after PZQ treatment, stimulated with egg antigen or media; FibroPlex analytes were measured in supernatants with a multiplexed assay. Antigen-specific cytokine levels were evaluated for their relationship with liver span measured by ultrasound in right parasternal line. Potential confounders included baseline liver span, sex, socioeconomic status, cumulative water contact, egg counts at baseline and 1 year after treatment, height, and hepatitis B antigenemia. Error bars represent standard error of the mean.