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. Author manuscript; available in PMC: 2011 Apr 8.
Published in final edited form as: Methods Enzymol. 2009;467:547–581. doi: 10.1016/S0076-6879(09)67021-X

Figure 7.

Figure 7

Simulated progressive decline of the ability of glucose to suppress glucagon resulting from a gradual transition (same as in Figure 6) from a normal physiology (top) to an insulinopenic state (bottom).