Table I.
Rate Constant | Dose-Response Control Functions | ||||
---|---|---|---|---|---|
Elimination [1/hour] |
Release [concentration/hour] |
ED50, or ID50 [concentration] |
Slope [dimension- less] |
Delay [min] |
|
Glucagon | kGL = 22 h−1 |
rGL = 42,570pg/mL/h rGL,basal = 2,128pg/mL/h |
tGL = 85pg/mL | nGL = 5 | DGL = 7.2min |
BG |
tBG = 50mg/dL tBG,2 = 400mg/dL |
nBG = 5 nBG,2 = 3 |
|||
Insulin | kINS = 14h−1 |
rINS = 80,000 rINS,basal = 270 |
tINS = 20 | ||
Pulse | periodic function: a square wave of height = 10 over a period of 36 sec recurring every 6 minutes |