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. Author manuscript; available in PMC: 2012 Mar 15.
Published in final edited form as: J Immunol. 2011 Feb 4;186(6):3615–3621. doi: 10.4049/jimmunol.1002952

FIGURE 1.

FIGURE 1

Live and dead organisms induce different protection against C. muridarum genital tract infection. Mice were vaccinated with live EBs or dead EBs with or without CpG via intranasal route as described in Materials and Methods. Mice were intravaginally challenged with 1500 IFU live C. muridarum after immunization with a variety of vaccine formulations. Cervicovaginal washes were taken at day 6 after challenge, and bacterial titers were measured on HeLa 229 cells. *p < 0.01, **p < 0.001 in comparison with the corresponding nonimmunization (naive) group. D-EB, dead EBs; L-EB, live EBs.