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Kinetic analysis of 17-dihydroexemestane glucuronidation by individual HLM specimens from subjects stratified by UGT2B17 genotype.
| HLM # | UGT2B17 genotype | Vmax(pmol·min−1·mg−1) | Km(μM) | Vmax/Km(μL·min−1·mg−1) |
|---|---|---|---|---|
| 972 | *1/*1 | 51.6 | 10.6 | 4.9 |
| 1603 | *1/*1 | 20.2 | 7.4 | 2.7 |
| 4118 | *1/*2 | 63.6 | 12.1 | 5.3 |
| 1270 | *1/*2 | 7.6 | 10.2 | 0.75 |
| 416 | *2/*2 | 5.6 | 17.2 | 0.33 |
| 145 | *2/*2 | 7.5 | 23.3 | 0.32 |
