TABLE 3.
Comparison of age-adjusted odds of advanced disease status among prostate cancer cases, stratified by patient characteristics (OR, 95% CI)
| Group | T3/T4 tumor stage | Gleason ≥ 7 | Positive for metastasis | |||||||||
|---|---|---|---|---|---|---|---|---|---|---|---|---|
| EA | AA | SEN | EI | EA | AA | SEN | EI | EA | AA | SEN | EI | |
| Total sample |
1.00 | 0.8 (0.6-1.0) |
2.9 (1.8-4.7) |
344.7 (47.9-2482) |
1.00 | 0.8 (0.6-1.1) |
0.9 (0.5-1.5) |
2.9 (1.9-4.4) |
1.00 | 3.2 (1.1-9.3) |
* | 377.1 (166-858) |
| 1.00 | 3.8 (2.2-6.7) |
458.2 (62.6-3353) |
1.00 | 1.1 (0.6-1.9) |
3.5 (2.2-5.6) |
1.00 | * | 118.0 (46.9-297) |
||||
| 1.00 | 119.2 (15.8-902) |
1.00 | 3.2 (1.7-6.0) |
* | * | |||||||
| Age < 62 | 1.00 | 0.8 (0.5-1.3) |
4.0 (1.5-10.9) |
103.0 (14.0-756) |
1.00 | 1.01 (0.7-1.5) |
0.6 (0.2-1.9) |
3.0 (1.5-5.9) |
1.00 | 8.1 (1.5-44.6) |
* | 808.3 (167-3923) |
| 1.00 | 4.9 (1.7-14.1) |
125.4 (16.6-947) |
1.00 | 0.6 (0.2-1.9) |
3.0 (1.4-6.2) |
1.00 | * | 100.2 (29.0-346) |
||||
| 1.00 | 25.5 (2.8-232) |
1.00 | 4.7 (13-16.8) |
* | * | |||||||
| Age ≥ 62 | 1.00 | 0.7 (0.4-1.1) |
2.4 (1.4-4.4) |
* | 1.00 | 0.7 (0.5-1.0) |
1.0 (0.6-1.9) |
2.9 (1.7-4.9) |
1.00 | 1.6 (0.3-8.0) |
* | 280.6 (104-759) |
| 1.00 | 3.7 (1.8-7.4) |
* | 1.00 | 1.5 (0.8-2.9) |
4.2 (2.3-7.7) |
1.00 | * | 176.1 (38.9-796) |
||||
| 1.00 | * | 1.00 | 2.8 (1.3-6.0) |
* | * | |||||||
| Family history negative |
1.00 | 0.8 (0.5-1.2) |
3.5 (1.9-6.2) |
320.1 (44.4-2310) |
1.00 | 0.7 (0.5-1.0) |
0.8 (0.4-1.4) |
2.5 (1.6-3.9) |
1.00 | 4.7 (1.2-19.1) |
* | 443.8 (151-1303) |
| 1.00 | 4.2 (2.2-8.2) |
388.0 (523-2880) |
1.00 | 1.1 (0.6-2.1) |
3.5 (2.1-5.9) |
1.00 | * | 93.9 (31.7-278) |
||||
| 1.00 | 92.1 (11.9-711) |
1.00 | 3.2 (1.6-6.6) |
* | * | |||||||
| Family history positive |
1.00 | 0.6 (0.3-1.0) |
1.1 (0.3-3.6) |
* | 1.00 | 0.8 (0.5-1.4) |
1.2 (0.4-3.7) |
* | 1.00 | 1.1 (0.1-10.1) |
* | 220.3 (15.3-3181) |
| 1.00 | 2.0 (0.6-7.3) |
* | 1.00 | 1.5 (0.5-4.6) |
* | 1.00 | * | 198.9 (8.0-4939) |
||||
| 1.00 | * | 1.00 | * | * | * | |||||||
| PSA < 10 | 1.00 | 0.5 (0.3-0.8) |
8.7 (0.8-97.6) |
* | 1.00 | 0.6 (0.4-0.8) |
0.7 (0.1-7.6) |
* | 1.00 | 4.7 (0.9-23.6) |
* | * |
| 1.00 | 17.0 (1.5-197) |
* | 1.00 | 1.2 (0.1-13.6) |
* | 1.00 | * | * | ||||
| 1.00 | * | 1.00 | * | * | * | |||||||
| PSA ≥ 10 | 1.00 | 1.1 (0.6-1.9) |
1.6 (0.9-2.9) |
185.2 (25.3-1356) |
1.00 | 1.4 (0.8-2.6) |
0.5 (0.3-1.0) |
1.7 (1.0-2.7) |
1.00 | 3.4 (0.7-17.5) |
* | 186.7 (55.1-632) |
| 1.00 | 1.4 (0.7-3.0) |
166.0 (21.7-1268) |
1.00 | 0.4 (0.2-0.8) |
1.2 (0.6-2.2) |
1.00 | * | 54.3 (15.7-187) |
||||
| 1.00 | 116.2 (15.1-895) |
1.00 | 3.3 (1.6-6.7) |
* | * | |||||||
*
Could not be estimated