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Stimulated C-peptide and proinsulin over time according to PTPN22 genotypes. The association of stimulated C-peptide (A.) and proinsulin (B.) level 1, 6 and 12 months after disease onset by PTPN22 genotype (homozygous+heterozygous (CT+TT) (n = 71) carriers of the variant versus wildtype (CC) (n = 186)). Mean values (pmol/l) ± SEM.
