Table 2.
Analysis of association between APE1/Ref-1 rs1760944 and risk of all gliomas
| rs1760944 | Controls (824) | All Gliomas (766) | |||
|---|---|---|---|---|---|
| No. (%) | No. (%) | Pa | OR (95% CI) b | Pc | |
| Alleles | |||||
| T | 898 (55.0) | 858 (57.2) | 0.220 | 1.00 (reference) | 0.220 |
| G | 734 (45.0) | 642 (42.8) | 0.91 (0.79-1.05) | ||
| Genotypes | |||||
| TT | 237 (29.0) | 233 (30.4) | 0.410 | 1.00 (reference) | |
| TG | 424 (52.0) | 392 (51.2) | 0.94 (0.75-1.18) | 0.588 | |
| GG | 155 (19.0) | 125 (16.3) | 0.81 (0.61-1.10) | 0.183 | |
| Pd for trend = 0.199 | |||||
aAllele and genotype frequencies in cases and controls were compared using χ2 test.
bAllele-specific OR was not adjusted; genotype-specific ORs were adjusted for age and gender.
cP value from unconditional logistic regression analyses.
dTrend test was calculated using the genotype as an ordinal variable in the regression model.