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. 2011 Apr 8;6(4):e18469. doi: 10.1371/journal.pone.0018469

Figure 1. Changes in Na+ channel associated parameters post-oxaliplatin in motor axons.

Figure 1

A) Refractoriness pre (black bars) and post (white bars) single oxaliplatin infusion demonstrating significant change post-oxaliplatin in motor axons (Refractoriness Pre: 31.7±6.4%; Post 68.8±14.5%; P≤.001). B) Strength-duration time constant pre (black bars) and post (white bars) oxaliplatin infusion, demonstrating unchanged results following oxaliplatin treatment (Pre: 0.395±0.01 ms; Post: 0.394±0.02 ms; NS). C) Inset diagram of the changes in the recovery cycle of excitability pre- (black circles) and post-oxaliplatin infusion (white circles) for all patients, with error bars representing standard error of the mean and refractoriness outlined by a box and an arrow demonstrating direction of change.