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. 2011 Apr 8;6(4):e18436. doi: 10.1371/journal.pone.0018436

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Cerchietti et al.

This is an open-access article distributed under the terms of the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original author and source are properly credited.

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A: Determination (from top to bottom) of ALK, CD138, CD30 and Ig kappa chain expression and distribution by immunohistochemistry in the original tumor (left column), LM1 cell line grown in vitro (middle column) and LM1 xenografted tumor in NOD-SCID mice (right column). B: The expression of CD30 (left column) and ALK (right column) were determined by flow cytometry in the LM1 cell line before and after engraftment in the NOD-SCID mouse model. The ALCL cell line SU-DHL1 was used as positive control for CD30 and ALK expression while the BL cell line DG75 served as negative control.