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. Author manuscript; available in PMC: 2012 Apr 30.
Published in final edited form as: Mol Cell Endocrinol. 2011 Jan 26;337(1-2):16–23. doi: 10.1016/j.mce.2011.01.016

Figure 3.

Figure 3

Inositol phosphate (IP) dose-response curves for Buserelin in cultured COS-7 cells transiently expressing the WT and hGnRH mutant receptors (A), or hGnRHRs lacking Lys191 (B) or bearing the catfish C-tail (C). The graphs also include IP production in cells cotransfected with the Thr104Ile and Tyr108Cys mutants with or without the genetic modifications imposed. Results are the means ± SEM of 3 or more experiments in triplicate incubations.