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. 2010 Nov 15;22(4):489–497. doi: 10.1089/hum.2010.159

Table 2.

Summary of Product Yield During Pilot Lot Production

Sample ID Volume Infectious titer (PFU/ml) Total infectious units (PFU)
Clarified supernatant 9 liters 2.4 × 108 2.2 × 1012
Post-Benzonase 9 liters 6.0 × 108 5.4 × 1012
Elution peak (1.2M) 312 ml 1.7 × 108 5.3 × 1011
Post-UF/DF 105 ml 5.2 × 109 6.0 × 1011
Formulated bulk 116 ml 7.2 × 109 8.4 × 1011
Filtered (0.2 μm) 100 ml 1.2 × 1010 1.3 × 1012

DF, diafiltration; UF, ultrafiltration.