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. Author manuscript; available in PMC: 2012 Jul 1.
Published in final edited form as: Brain Behav Immun. 2010 Nov 11;25(5):1000–1007. doi: 10.1016/j.bbi.2010.11.003

Figure 5. Tissue Pathology following Clostridium sordellii exposure.

Figure 5

Histopathological analysis of C57BL/6 mice administered C. sordellii lethal toxin (CsL) intraperitoneally. was assessed 12 hours following exposure. Micrographs (600× magnification, inset - 100× magnification) show lymphoid depletion in spleen tissue (A) and apoptosis in thymus tissue (B) that was not identified in control (saline-treated) animals. (C) Graphs show percentage of control and infected mice exhibiting alterations in lymphoid architecture. Mean ± SEM * = p<0.05 (n=5 mice/group)