Table 1.
Demographic and Clinical Characteristics and Mood and Anxiety Ratings in Depressed and Healthy Women
| Characteristic | HC mean (sd) |
MDD mean (sd) |
|---|---|---|
| Age (years) | 34.4 (4.5) | 34.2 (4.4) |
| Ethnicity (% Caucasian) | 100 | 100 |
| Handedness (% right-handed) | 100 | 100 |
| Verbal IQ1 | 14.3 (3.1) | 14.2 (1.3) |
| Age of symptom onset (years) | N/A | 20.9 (5.0) |
| Duration of illness (years) | N/A | 13.3 (8.5) |
| Number of episodes | N/A | 2.9 (1.9) |
| HAM-D score2 | N/A | 3.5 (2.5) |
| Mood Scale3 | ||
| Vigor4 | ||
| Pre-scan | 63.8 (8.3) | 56.5 (9.0) |
| Post-scan | 56.8 (14.0) | 55.8 (4.1) |
| Anxiety Scale5 | ||
| Trait Anxiety6 | 31.3 (8.8) | 39.3 (7.6) |
| State Anxiety7 | ||
| Pre-scan | 28.7 (5.9) | 32.5 (7.2) |
| Post-scan | 32.7 (7.0) | 33.7 (7.2) |
Scaled scores from WAIS Vocabulary subtest
Hamilton Depression Rating Scale (17-item)
Profile of Mood States (POMS) rates current mood (self-report); consists of 72 items, rated on a scale from 0 to 4 (0 = does not apply; 4 = the adjective describes emotional state extremely well). Table reflects a standardized mood state score for the Vigor subscale only; there were no significant within- or between-group differences on the other 5 subscales (Anxiety, Depression, Anger, Fatigue, Confusion); any score < 50 is in the low, normative range.). The POMS was not collected for one HC woman.
Significant within-group pre-scan to post-scan difference in the healthy control group, p<0.05, two-tailed
Spielberger State-Trait Anxiety Inventory (STAI) is a self-report of current and “usual” levels of anxiety. 40 statements are rated on a scale from 1 to 4 (1 = statement poorly reflects feelings of anxiety; 4 = statement accurately reflects feelings of anxiety). Statements reflect how the individual feels in general (reflecting trait-level anxiety) and current feelings of anxiety (reflecting state-level anxiety), out of which a standardized overall rating is also calculated. Any score < 50 is in the low normative range.
Significant between-group difference, p<0.05, two-tailed
Significant within-group pre-scan to post-scan difference in the healthy control group, p<0.05, two-tailed