Table 5.
Pooled Multivariate Relative Risks1 and 95% Confidence Intervals for Body Mass Index by Levels of Other Pancreatic Cancer Risk Factors
Factor | BMI at Baseline (5kg/m2) |
P-value,heterogeneity2 | P-value,interaction3 | BMI in Early Adulthood (5kg/m2) |
P-value,heterogeneity2 | P-value,interaction3 | ||
---|---|---|---|---|---|---|---|---|
Cases | Continuous RR(95% CI) |
Cases | Continuous RR (95% CI) |
|||||
Overall | 2135 | 1.14(1.07–1.21) | 0.24 | 1598 | 1.20(1.10–1.30) | 0.62 | ||
Sex | ||||||||
Females | 1116 | 1.13(1.06–1.21) | 0.39 | 0.90 | 918 | 1.14(1.02–1.28) | 0.37 | 0.23 |
Males | 1019 | 1.14(1.01–1.29) | 0.13 | 680 | 1.27(1.12–1.44) | 0.88 | ||
Smoking Status | ||||||||
Never4–5 | 748 | 1.19(1.08–1.31) | 0.20 | 0.12 | 628 | 1.28(1.12–1.46) | 0.52 | 0.11 |
Past4,6 | 642 | 1.22(1.10–1.34) | 0.73 | 548 | 1.30(1.13–1.50) | 0.58 | ||
Current7 | 628 | 1.07(0.95–1.21) | 0.25 | 338 | 1.02(0.84–1.23) | 0.50 | ||
Physical Activity8–9 | ||||||||
Low | 825 | 1.13(1.00–1.28) | 0.002 | 0.02 | 652 | 1.14(1.00–1.30) | 0.75 | 0.31 |
Medium | 587 | 1.15(1.04–1.28) | 0.57 | 458 | 1.16(0.99–1.36) | 0.78 | ||
High | 473 | 1.29(1.15–1.45) | 0.80 | 397 | 1.31(1.11–1.55) | 0.60 | ||
Median Age at Diagnosis (years) | ||||||||
<69 | 1042 | 1.15(1.07–1.25) | 0.35 | 0.82 | 749 | 1.19(1.05–1.33) | 0.58 | 0.91 |
≥69 | 1093 | 1.14(1.05–1.22) | 0.78 | 849 | 1.20(1.07–1.35) | 0.57 | ||
Follow-up Time (years) | ||||||||
< 5 10–11 | 726 | 1.20(1.10–1.31) | 0.50 | 0.24 | 511 | 1.12(0.96–1.31) | 0.38 | 0.26 |
≥5 | 1394 | 1.12(1.05–1.20) | 0.47 | 992 | 1.23(1.12–1.36) | 0.95 |
See Table 2 for adjustment factors. The stratification variable was excluded from the model.
P-value, test for between-studies heterogeneity
P-value, test for interaction
ATBC was excluded from the never and past smoking analyses because this study only included current smokers.
NLCS(Males) was excluded from this strata due to small case numbers (n<10)
MCCS(Females) was excluded from this strata due to small case numbers (n<10)
MCCS(Males and Females) were excluded from this strata due to small case numbers (n<10)
NYSC(Female and Males) was excluded from the physical activity analysis since they did not measure physical activity.
CNBSS was excluded from the physical activity analysis for BMI in early adulthood due to small case numbers (n<10).
MCCS(Females) were excluded from this strata due to small case numbers (n<10)
MCCS(Males) were excluded from this strata due to small case numbers(n<10)