Table 1.
Changes in Y2 receptor binding in presumed target areas of efferent projections of the CEA after Y2 gene deletion in the CEA
Brain area | % of control ± SEM |
---|---|
Ncl. accumbens, core | 80.4 ± 5.00 |
Ncl. accumbens, shell | 64.0 ± 4.96* |
Lateral septum | 87.0 ± 6.31 |
Stria terminalis/bed nucleus of stria terminalis | 81.2 ± 3.01* |
Central amygdala | 62.5 ± 4.16*** |
Lateral hypothalamus | 102.4 ± 3.88 |
Ventral hippocampus (CA1) | 95.8 ± 3.80 |
Periaqueductal gray | 96.6 ± 5.21 |
Locus ceruleus | 75.2 ± 3.04* |
[125I]hPYY3-36 was determined 4 weeks after rAAV-Cre injection (n = 16) into the CEA and compared with rAAV-GFP-injected mice (n = 10). Stringent statistical testing by ANOVA and Bonferroni post hoc test was used.
*p < 0.05,
***p < 0.001.