Table 2.
Contexts summary
| Contexts | Samples | Genes | ER +/ ER- | PgR+/PgR- | LN+/LN- | Grade | Subtypes |
|---|---|---|---|---|---|---|---|
| C 89 | 1418 | 2 | ER+ | PgR+ | Low | Normal, LumA | |
| C 16 | 1330 | 16 | ER+ | PgR+ | Low | Normal, Her2, LumB, LumA | |
| C 75 | 1200 | 4 | |||||
| C 34 | 1186 | 23 | LN+ | ||||
| C 68 | 1068 | 4 | |||||
| C 40 | 1044 | 6 | LN+ | Low | LumA | ||
| C 57 | 824 | 7 | LN+ | High | Basal | ||
| C 73 | 805 | 3 | PgR+ | LN- | High | LumB | |
| C 51 | 788 | 6 | ER+ | PgR+ | Low | Normal, LumA | |
| C 18 | 738 | 10 | ER- | PgR- | LN+ | High | Normal, Basal |
| C 67 | 731 | 4 | |||||
| C 79 | 658 | 2 | ER+ | PgR+ | Low | Normal, LumB, LumA | |
| C 55 | 551 | 6 | LN- | High | |||
| C 49 | 549 | 6 | LN- | ||||
| C 150 | 395 | 5 | ER- | PgR- | LN+ | High | Basal, Her2 |
| C 126 | 336 | 2 | LN- | Low | LumA | ||
| C 162 | 248 | 2 | ER- | PgR- | High | Basal, Her2 | |
| C 134 | 234 | 4 | ER- | PgR- | High | Basal, Her2 | |
| C 160 | 202 | 2 | ER- | PgR- | High | Basal | |
| C 48 | 188 | 27 | ER- | PgR- | High | Basal | |
| C 121 | 186 | 2 | Normal | ||||
| C 143 | 185 | 4 | ER+ | LN- | High | ||
| C 147 | 175 | 3 | LN- | High | LumB | ||
| C 168 | 154 | 5 | ER- | PgR- | LN- | High | Basal |
| C 146 | 153 | 2 | LN- | High | |||
| C 110 | 152 | 5 | ER- | PgR- | High | Basal | |
| C 145 | 150 | 9 | ER- | LN- | High | Basal | |
| C 159 | 150 | 3 | ER- | Basal | |||
| C 130 | 129 | 2 | ER- | PgR- | High | Basal | |
| C 124 | 128 | 2 | LN- | High | LumB | ||
| C 131 | 126 | 2 | ER+ | PgR+ | Low | Normal, LumA | |
| C 28 | 121 | 10 | LN+ | Low | Normal | ||
| C 155 | 119 | 3 | ER- | High | Basal | ||
| C 50 | 118 | 42 | ER+ | LumA | |||
| C 153 | 115 | 5 | Normal | ||||
| C 139 | 111 | 2 | |||||
| C 104 | 95 | 5 | |||||
| C 144 | 90 | 7 | LN- | High | |||
| C 22 | 86 | 31 | ER- | PgR- | LN+ | High | Basal, Her2 |
| C 115 | 86 | 2 | ER+ | PgR+ | LN+ | Low | Normal, LumA |
| C 111 | 84 | 4 | ER- | PgR- | High | Basal, |
Results show contexts (ordered by number of samples) obtained after context-motif mining and MCL in column 1; contexts samples associated with a threshold 0.7 and specificity of 2 in column 2 and context genes in column 3. Context enrichments with clinical and molecular features (ER Status, PgR Status, Grade and LN Status) are shown in columns 4-7, selected after a statistical significance of < 0.05 (Low Grade =Grades 1 and 2; High Grade = Grade 3). Last column shows intrinsic subtype enrichments with LumA=Luminal A, LumB= Luminal B, Basal = Basal-like , Her2 and normal Tumors.