Figure 2.

mtDNA structure of Cryptococcus: all the mtDNAs show a conserved gene synteny but have different sizes. (A) IFM5844 (C. neoformans var. neoformans, serotype D) and (B) IFO410 (C. neoformans var. grubii, serotype A). These two mtDNA structures were drawn to scale based on information from litter et al.;³⁷ (C) mtDNA structure of A1M-R265 (C. gattii, VGII). Sections with light blue colour are either introns or intergenic spaces;⁵ (D) Circular mtDNA structure of JEC21 (C. neoformans var. neoformans) and H99 (C. neoformans var. grubii) (taken from Toffaletti et al.¹⁶); (E) Simple alignment of A1M-R265 and WM276 (C. gattii, VGI) mtDNA using ClusterW. Before alignment, two repeat regions in both mtDNAs were removed (region one: 2434 nucleotides in COX1 gene; region two: 963 nucleotide at the end of the supercontig). Sections with white color stand for the variations between two mtDNA sequences.