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Landmarks in heart development in the models discussed in this review
| Zebrafish (hpf) |
Frog (N&F) |
Chick (HH) |
Mouse (dpc) |
Human (days) |
|
|---|---|---|---|---|---|
| Gastrulation | 5.5 | 10 | 4 | 7 | 15-16 |
| Heart fields | 13 | 24 | 5 | 7 | 18 |
| Heart trough | 19 (cone) | 29/30 | 9 | 8 | 21-23 |
| Heart tube | 22 | 32/33 | 11 | 8.5 | 24 |
| Looping | 24-48 | 33-35 | 14-18 | 8.5-10.25 | 24-25 |
| Myocardial contraction |
22 | 32/33 | 10 | 8.5 | 24 |
| Anterograde circulation |
24 | 37 | 14 | 9 | 25 |
| Venous pole addition |
24-72 | ND | 14-18 | 8.5-10.25 | 25-40 |
| Proepicardium | 50 | 41 | 15 | 9.5 | 28-35 |
