Table 3.
Functional outcome scale* | Responders |
Non-responders |
** F | ** df | p-value | ||
---|---|---|---|---|---|---|---|
Baseline | Endpoint | Baseline | Endpoint | ||||
* Physical SF-12 | 45.7 (±9.9) | 44.3 (±10.0) | 41.6 (±10.5) | 42.2 (±10.9) | 6.21 | 1,150 | 0.791 |
* Mental SF-12 | 42.3 (±11.1) | 50.4 (±8.7) | 39.1 (±10.7) | 41.3 (±9.7) | 33.22 | 1,149 | 0.000 |
* SSPA | 32.6 (±6.6) | 32.6 (±6.4) | 31.7 (±6.7) | 31.7 (±6.8) | 0.23 | 1,134 | 0.632 |
* MMAA total errors | 9.4 (±7.8) | 8.4 (±7.7) | 8.1 (±5.5) | 7.5 (±5.8) | 0.15 | 1,131 | 0.697 |
* QOLS | 58.0 (±22.8) | 64.5 (±23.2) | 57.7 (±20.9) | 57.8 (±24.2) | 5.18 | 1,134 | 0.024 |
Values represent means with standard deviation in parentheses.
Physical SF-12 = physical component of the medical outcomes study short form SF-12; Mental SF-12 = mental component of the SF-12; SSPA = social skills performance assessments; MMAA total errors = total number of medication errors on the medication management ability assessments; QOLS = Quality of Life Scale.
F values with degrees of freedom (df) derived from analysis of covariance. Outcome at the study end point was the dependent variable. Treatment group, site, baseline severity, and treatment group by site interaction were included as independent variables.