Confirmatory PCR was performed using genomic DNA as the template from wild type and transfected parasite clones. PCR products obtained at the 5′ junction from (A) primers DP1::DP2; (B) DP1::DP3; and at the 3′ junction of the altered chromosome with primers; (C) DP4::DP5; and (D) DP4::DP6. Lane 1: positive clone B6, Lane 2: positive clone C4, Lane 3: negative clone B7, Lane 4: wild type RH genomic DNA, Lane 5: p25.m01787MSG plasmid, Lane 6: No DNA control, and Lane 7: DNA ladder.