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. Author manuscript; available in PMC: 2012 Feb 1.
Published in final edited form as: Nanomedicine. 2010 Aug 6;7(1):1–10. doi: 10.1016/j.nano.2010.07.002

Table 4.

Effect of lyophilization of fresh tumor-derived lysate on encapsulation. Limited availability of fresh tumor material resulted in a relatively dilute lysate. However lyophilization enabled increase in the extent of encapsulation.

Protein concentration of lysate (μg/μl) Volume of lysate (μl) Type of lysate* Protein content of starting lysate (μg) Weight of NP used for encapsulation (mg) Protein content of NP (μg/mg) Encapsulation efficiency (%)
32.5 50 S 1625 50 14 43.1%
23 100 L 2300 50 19.6 42.6%
*

S= Soluble; L=Lyophilized