. Author manuscript; available in PMC: 2012 Mar 15.

Published in final edited form as: J Am Coll Cardiol. 2011 Mar 15;57(11):1271–1279. doi: 10.1016/j.jacc.2010.09.074

Table 3.

Percent decrease in inflammatory biomarkers per one unit increase in CFR, in the entire myocardium and in regional coronary artery territories.

	Entire Myocardium		Left Anterior Descending		Circumflex		Right Coronary Artery
	%	P	%	P	%	P	%	P
CRP (mg/L)	17.0	0.03	16.6	0.03	18.5	0.009	15.4	0.05
IL-6 (pg/dL)	14.5	0.01	13.6	0.008	16.1	<0.001	13.3	0.01
WBC (1000/μL)	4.5	0.02	4.7	0.01	4.3	0.01	4.5	0.02
ICAM-1 (ng/mL)	3.5	0.08	2.9	0.12	2.5	0.17	2.7	0.16
VCAM-1 (ng/mL)	3.1	0.22	2.5	0.27	1.5	0.48	2.4	0.31

CRP: C-reactive protein; IL-6: interleukin-6; WBC: white blood cell count; VCAM-1: vascular cell adhesion molecule-1; ICAM-1: intercellular adhesion molecule-1.

Values are derived from mixed models with log-transformed biomarker data. Percentages are calculated from regression coefficients.