Table 4.
Adjusted associations between maternal anemia and childhood wheeze patterns, all children combined and by maternal asthma status1
Wheeze Pattern2 | All children | Non-asthmatic mothers | Asthmatic mothers | |||
---|---|---|---|---|---|---|
ORa | 95% CI | ORa | 95% CI | ORa | 95% CI | |
No wheeze | ref | ref | ref | |||
Early-onset, transient | 2.76 | 1.35–5.64 | 3.90 | 1.43–10.6 | 2.56 | 0.77–8.50 |
Late-onset | 0.77 | 0.22–2.65 | NAC3 | 0.72 | 0.11–4.60 | |
Early-onset, persistent | 1.96 | 0.95–4.03 | 1.18 | 0.35–4.04 | 3.67 | 1.27–10.6 |
Adjusted for child's gender, race, # children in household at age 6, maternal allergies, maternal education, pre-pregnancy BMI, maternal smoking in 1st trimester, folate supplementation in first trimester, NICU admission, preterm delivery, SGA, # months breastfed, smoking in household in years 1 and 5, daycare attendance in year 1, pets in years 1 and 5, mold in years 1 and 5.
Early-onset transient wheeze=wheeze onset <3 years but no symptoms by age 6; late-onset wheeze=wheeze ≥3 years; early-onset persistent wheeze=wheeze <3 years and wheeze at age 6
NAC (not able to calculate)