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. Author manuscript; available in PMC: 2012 Mar 1.
Published in final edited form as: J Card Fail. 2010 Dec 24;17(3):253–263. doi: 10.1016/j.cardfail.2010.10.008

Table 1.

Echocardiography Data of WT, A1-TGcon and A1-TGind Mice

WT (10wks) A1-TGind (10wks) A1-TGind (26wks) A1-TGcon (10wks)
N 8 10 6 5
HR (bpm) 441 ± 16 316 ± 24** 151 ± 7** 162 ± 13**
FS% 46.5 ± 1.7 49.2 ± 2.6 29.7 ± 1.6* 16.8 ± 4.7**
LVEDD (mm) 2.84 ± 0.11 3.18 ± 0.11 4.91 ± 0.24** 4.91 ± 0.21**
LVESD (mm) 1.53 ± 0.08 1.64 ±0.13 3.45± 0.24** 4.10 ± 0.36**

Echocardiography of male wild type and mice constitutively expressing A1-AR (A1-TGcon) and after DOX was removed from their diet at 3 weeks to induce myocardial A1-AR expression (A1-TGind). Echocardiography data: HR, heart rate; FS%, percent fractional shortening; LVEDD, LV end-diastolic dimension in mm; LVESD, LV end-systolic dimension in mm. Values are means +/− SEM.

*

P<0.01 vs. WT and

**

P<0.001 vs. WT