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. 2010 Nov 24;30(47):16044–16052. doi: 10.1523/JNEUROSCI.6364-09.2010

Figure 5.

Figure 5.

HEPES does not inhibit postsynaptic GABAergic transmission. A1–A5, CGC whole-cell response to rapid application of 100 μm GABA in 3 mm HEPES at pH 7.4 (control), 24 mm HEPES at pH 7.4, 3 mm HEPES at pH 6.0, 24 mm HEPES at pH 6.0, and back to control. B1–B5, CGC whole-cell response to rapid application of 100 μm GABA in 3 mm HEPES at pH 7.4 (control), 24 mm HEPES at pH 7.4, 3 mm HEPES at pH 6.8, 24 mm HEPES at pH 6.8, and back to control. C, Standardized charge transfer evoked by 100 μm GABA in 3 and 24 mm HEPES at the three pH values relative to control. n = 7 neurons at pH 7.4, n = 3 at pH 6.0, n = 4 at pH 6.8. † p < 0.001.