Fig. 1. Role of hsp70 in short term hypoxia (days).
Flies with tissue specific overexpression of Hsp70 were obtained by crossing UAS-hsp70 with various tissue specific Gal4 drivers. Progeny from these crosses along with Canton-S (CS) and yellow white (yw) serving as controls were exposed to 1.5 % O2 (constant hypoxia) and survival was scored every day. Flies with Hsp70 overexpression in the heart (Hsp70Bbb/handGal4) and brain (Hsp70Bbb/P{GawB}c739) have a remarkably increased survival in 1.5% O2 compared to control flies. * indicates p < 0.05 and *** indicates p < 0.001 (Azad et al., 2009).