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Crude mean total testosterone concentrations, by MMAS study wave (T1, T2, T3), with confidence bands (dotted lines). Estimates are obtained from a generalized additive model with a lowess smoothing term. Source: MMAS, Travison et al., J Clin Endocrinol Metab 2007; 92(1):196–202. 72 Copyright 2007, The Endocrine Society. Used with permission.
