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Schematic of BK channel structure. Top, S0–S6 are transmembrane segments, and RCK1 and RCK2 are located in cytoplasm. PGD, Pore-gate domain. Star (★) represents the location of Ca2+ binding sites. The sequence and secondary structure of the N terminus including S0 and the C-Linker and AC region are shown below. Asterisk (*) identifies conserved residues.
