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Response of S. aureus NCTC 8325 (a–d) and the prophage-cured derivative RN4220 (e–h) to subinhibitory and supra-inhibitory concentrations of ELB-21 and mitomycin C (MMC). ELB-21 (a, b, e, f) and MMC (c, d, g, h) were added to mid-logarithmic phase cultures (OD600 ≈ 0.1; 2 h), OD600 measured (a, c, e, g) and viable numbers determined (b, d, f, h). Error bars represent ±1 SD; n = 3.
