Table 1.

15-HETE, 12-HETE and 5-HETE production in pulmonary artery from male and female rabbits

	15-HETE (pg/mg)		12-HETE (pg/mg)		5-HETE (pg/mg)
SEX	Basal	+A23187	Basal	+A23187	Basal	+A23187
Male	707 ± 220	1506 ± 522 *	226 ± 66	841 ± 254 *	30 ± 8	190 ± 46 *
Female	1713 ± 538 †	4097 ± 921 *†	240 ± 29	621 ± 102 *	30 ± 7	251 ± 28 *

Segments of pulmonary arteries from male and female rabbits were incubated with and without A23187 (20 μMol/L) for 15 minutes at 37°C. The production of 15-, 12- and 5-HETE were measured in the incubation media using LC/ESI/MS. Values are mean ± SEM for n = 6.

^*p < 0.05, Basal vs A23187;

^†p < 0.05 Female vs Male