. Author manuscript; available in PMC: 2012 Apr 1.

Published in final edited form as: Am J Obstet Gynecol. 2011 Feb 16;204(4):362.e1–362.e6. doi: 10.1016/j.ajog.2010.12.013

Table 1.

DNA concentrations and yield in entire and partial samples of umbilical cord blood and buccal swabs.

Method of DNA Collection	Umbilical Cord Blood (total sample, n=35)	Oragene® Buccal Swabs (total sample, n=20)	Umbilical Cord Blood (partial sample, n=30)	Oragene® Buccal Swabs (partial sample, n=11)
Mean DNA concentration (ng/μl; range)	209.0 ± 110.7^* (7.4–468.5)	6.9 ± 6.7^* (0.6–29.2)	70.0 ± 51.4^* (8.9–204.7)	11.3 ± 6.7^* (4.3–26.2)
Average Eluted DNA volume (μl)	540	600	200	100
Mean total DNA yield (μg; range)	116.5 ± 70.8^* (2.2–281.1)	4.2 ± 4.0^* (0.4–17.5)	14.0 ± 10.3^* (1.8–40.9)	1.1 ± 0.7^* (0.4–2.6)

Data are means ± standard deviation

P<0.001 for all comparisons of cord blood vs. buccal swab for DNA concentration and total DNA yield. P value also <0.001 comparing mean DNA concentration and total DNA yield between cord blood samples with portion of sample analyzed and entire sample analyzed and between buccal samples with portion of sample and entire sample analyzed.

+Entire sample of umbilical cord blood was between 1–5 ml. Entire sample of buccal swabs was between 2–3 ml. Partial sample of umbilical cord blood utilized 0.2 ml. Partial sample of buccal swabs utilized 0.5 ml.