Table 1.

Examples of pre-publication data release guidelines for different project types.

Project type	Pre-publication data release recommended	Pre-publication data release optional
Genome sequencing	Whole-genome or mRNA sequence(s) of a reference organism or tissue	Sequences from a few loci for cross-species comparisons in a limited number of samples
Polymorphism discovery	Catalogue of variants from genomic and/or transcriptomic samples in one or more populations	Variants in a gene, a gene family, or a genomic region in selected pedigrees or populations
Genetic association studies	Genome-wide association analysis of thousands of samples	Genotyping of selected gene candidates
Somatic mutation discovery	Catalogue of somatic mutations in exomes or whole- genomes of tumor and non-tumor samples	Somatic mutations of a specific locus or limited set of genomic regions
Microbiome studies	Whole-genome sequence of microbial communities in different environments	Sequencing of target locus in a limited number of microbiome samples
RNA profiling	Whole-genome expression profiles from a large panel of reference samples	Whole-genome expression profiles of a perturbed biological system(s)
Proteomic studies	Mass spectrometry datasets from large panels of normal and disease tissues	Mass spectrometry datasets from a well-defined and limited set of tissues
Metabolomic studies	Catalogue of metabolites in one or more tissues of an organism	Analyses of metabolites induced of a perturbed biological system(s)
RNAi or chemical library screen	Genome-wide screen of a cell line or organism analyzed for standard phenotypes	Focused screens used to validate a hypothetical gene network
3D structure elucidation	Large-scale cataloguing of 3D structures of proteins or compounds	3D structure of a synthetic protein or compound elucidated in the context of a focused project