Table 5. INTERACTION – REMODELING CHANGES BY BASELINE VIABILITY & TREATMENT GROUP.
SEVERELY REDUCED VIABILITY < 40% |
MODERATE RETAINED VIABILITY ≥ 40% |
||||||||||
---|---|---|---|---|---|---|---|---|---|---|---|
PCI§ | MED‖ | PCI | MED | ||||||||
(N = 13) | (N = 20) | (N = 42) | (N = 37) | Interaction | |||||||
n | Mean±SD | n | Mean±SD | p-value | n | Mean±SD | n | Mean±SD | p-value | p-value | |
LV ED Volume (ml) | |||||||||||
1 | 3 | ||||||||||
Baseline | 12 | 153.2±52.2 | 7 | 158.8±39.9 | 0.75 | 41 | 108.9±36.4 | 5 | 120.0±37.4 | 0.19 | 0.75 |
1 | 3 | ||||||||||
1 yr | 12 | 142.6±54.1 | 7 | 152.1±44.2 | 0.61 | 41 | 107.2±36.9 | 5 | 120.7±37.9 | 0.12 | 0.82 |
1 | 3 | ||||||||||
Change (1 yr-Baseline) | 12 | −10.7±26.1 | 7 | −6.7±19.2 | 0.64 | 41 | −1.7±30.3 | 5 | 0.74±25.3 | 0.71 | 0.90 |
p-value (within group) | 0.18 | 0.17 | 0.72 | 0.86 | |||||||
LV ES Volume (ml) | |||||||||||
1 | 3 | ||||||||||
Baseline | 12 | 88.4±44.8 | 7 | 100.5±36.7 | 0.43 | 41 | 57.2±29.5 | 5 | 59.1±30.0 | 0.35 | 0.70 |
1 | 3 | ||||||||||
1 yr | 12 | 82.7±48.0 | 7 | 92.8±36.2 | 0.52 | 41 | 52.7±27.8 | 5 | 59.1±30.0 | 0.34 | 0.80 |
1 | 3 | ||||||||||
Change (1 yr-Baseline) | 12 | −5.8±22.1 | 7 | −7.7±19.5 | 0.80 | 41 | 4.5±22.7 | 5 | 4.5±18.2 | 0.99 | 0.84 |
p-value (within group) | 0.39 | 0.12 | 0.21 | 0.15 | |||||||
Ejection Fraction (%) | |||||||||||
1 | 3 | ||||||||||
Baseline | 12 | 44.8±12.6 | 7 | 38.9±10.3 | 0.18 | 41 | 57.2±29.5 | 5 | 48.3±10.1 | 0.52 | 0.35 |
1 | 3 | ||||||||||
1 yr | 12 | 45.9±16.8 | 7 | 40.4±10.2 | 0.28 | 41 | 52.7±27.8 | 5 | 53.6±10.0 | 0.96 | 0.27 |
1 | 3 | ||||||||||
Change (1 yr-Baseline) | 12 | 1.2±8.6 | 7 | 1.5±5.9 | 0.89 | 41 | 4.5±22.7 | 5 | 5.3±7.6 | 0.32 | 0.68 |
p-value (within group) | 0.65 | 0.30 | 0.21 | <0.001 | |||||||
Wall Motion Score | |||||||||||
1 | 3 | ||||||||||
Baseline | 12 | 23.2±7.8 | 7 | 24.6±6.5 | 0.60 | 41 | 49.9±10.4 | 5 | 15.6±6.8 | 0.71 | 0.81 |
1 | 3 | ||||||||||
1 yr | 12 | 17.7±10.4 | 7 | 19.6±8.6 | 0.59 | 41 | 53.5±11.3 | 5 | 10.5±7.2 | 0.71 | 0.75 |
1 | 3 | ||||||||||
Change (1 yr-Baseline) | 12 | −5.5±7.7 | 7 | −5.0±6.1 | 0.84 | 41 | 3.7±6.5 | 5 | −5.1±5.8 | 0.96 | 0.89 |
p-value (within group) | 0.003 | <0.001 | <0.001 |
LV ED=left ventricular end-diastolic dimension,
LV ES =ventricular end-systolic dimension
WM=wall motion,
PCI=percutaneous coronary intervention,
MED=medical therapy alone,