TABLE 6.
Univariate and Multivariable predictors of Remodeling Changes (1 yr-BL*)
| LV ED†VOLUME | N | Parameter Estimate | p |
|---|---|---|---|
| Univariate Predictors | |||
| PCI‡ Treatment | 105 | 2.02 | 0.70 |
| BL ED Volume (continuous) | 105 | −0.19 | 0.002 |
| BL Viability (continuous) | 105 | 0.44 | 0.22 |
| BL Infarct Size (continuous) | 105 | −0.15 | 0.35 |
| Prior CHF§ | 105 | 40.49 | 0.03 |
| Current Smoker | 105 | −12.62 | 0.02 |
| Systolic BP‖< 140 mmHg | 105 | −15.75 | 0.05 |
| Killip Class II–IV Index MI | 105 | −18.21 | 0.004 |
| Mitral Regurgitation 1–4 | 66 | 12.39 | 0.02 |
| IRA LAD# | 105 | −17.99 | 0.001 |
| Fasting Glucose / 10 | 102 | 1.31 | 0.04 |
| Multivariable Model* | N | Parameter Estimate | p |
| PCI Treatment | 102 | −4.98 | 0.28 |
| BL ED Volume (continuous) | 102 | −0.15 | 0.01 |
| Current Smoker | 102 | −14.95 | 0.002 |
| Fasting Glucose / 10 | 102 | 1.76 | 0.002 |
| IRA LAD | 102 | −14.81 | 0.006 |
| LV ES** VOLUME | N | Parameter Estimate | p |
| Univariate Predictors | |||
| PCI Treatment | 105 | −0.80 | 0.84 |
| BL ES Volume (continuous) | 105 | −0.18 | 0.001 |
| BL Viability (continuous) | 105 | 0.21 | 0.44 |
| BL Infarct Size (continuous) | 105 | −0.13 | 0.27 |
| Killip Class II–IV Index MI | 105 | −11.39 | 0.02 |
| IRA LAD | 105 | −13.06 | 0.002 |
| Multivariable Model* | N | Parameter Estimate | p |
| PCI Treatment | 105 | −1.25 | 0.75 |
| BL ES Volume (continuous) | 105 | −0.18 | 0.001 |
| EJECTION FRACTION | N | Parameter Estimate | p |
| Univariate Predictors | |||
| PCI Treatment | 105 | 0.96 | 0.49 |
| BL EF†† (continuous) | 105 | −0.08 | 0.19 |
| BL Viability (continuous) | 105 | 0.18 | 0.05 |
| BL Infarct Size (continuous) | 105 | −0.03 | 0.54 |
| Female | 105 | 4.52 | 0.008 |
| Multivariable Model* | N | Parameter Estimate | p |
| PCI Treatment | 105 | −1.20 | 0.36 |
| BL EF (continuous) | 105 | −0.20 | 0.004 |
| BL Viability (continuous) | 105 | 0.29 | 0.005 |
| Female | 105 | 5.06 | 0.003 |
Univariate predictors include those with p<0.10 and forced BL variables. ALL MV models: p=0.01 to remain. Mitral Regurgitation NOT in initial MV models. With Mitral Regurgitation in model, no significant predictors found. EDV At p=.05 to remain in model, predictors also included Prior CHF.ESV: At p=.05 to remain in model, predictors also included current smoking, fasting glucose, LAD IRA, and diastolic BP. EF: Same results with p=.05.
BL=baseline,
LV ED=left ventricular end-diastolic dimension,
PCI=percutaneous coronary intervention,
CHF=congestive heart failure,
BP=blood pressure,
IRA LAD=infarct-related artery left anterior descending coronary artery,
LV ES=ventricular end-systolic dimension,
EF=ejection fraction