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. Author manuscript; available in PMC: 2012 Apr 1.
Published in final edited form as: J Rheumatol. 2011 Jan 15;38(4):652–657. doi: 10.3899/jrheum.100728

Table 2.

Relation between F2 rs3136516 genotypes and plasma prothrombin activity (PPA) in a subset of Caucasian SLE cases (analysis was performed regardless of F2 rs1799963 status as well as only in individuals with wild-type GG genotype for rs1799963).

Caucasian Americans*
rs3136516 All cases (n=117) Cases with GG genotype for rs1799963 (n=111)


Genotypes PPA Mean±SE** [NIH-U/ml (%)] PPA Mean±SE** [NIH-U/ml (%)]
AA 15.17 ± 0.88 (86.69 ± 5.05) 14.79 ± 0.88 (84.53 ± 5.00)
GA 15.65 ± 0.46 (89.45 ± 2.61) 15.62 ± 0.47 (89.28 ± 2.69)
GG 17.70 ± 1.01 (101.12 ± 5.76) 17.73 ± 1.00 (101.30 ± 5.73)
P** 0.039 0.015
*

Only successfully genotyped individuals with available PPA measurements were included in the table

**

Mean and p-values adjusted for age, BMI, and Warfarin use; p-values under additive genetic effect model